張煥宗(Huan-Tsung Chang)
張煥宗(Huan-Tsung Chang) |
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職稱 |
教授 |
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最高學歷 |
愛荷華州立大學博士 |
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電話: |
+886-3-211-8800 ext.3020 |
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傳真 |
+886-3-211-8700 |
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實驗室 |
奈米醫藥、感測器和催化劑實驗https://www.ch.ntu.edu.tw/~htchang/ |
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專長 |
分析化學和奈米科學 |
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研究方向及研究室特色 |
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我們團隊致力於綠色合成奈米材料,並將其應用於感測器、細胞影像、藥物、奈米酵素、奈米催化劑及新能源等。研究重點如下: (I) 金、銀、銅及碳奈米點光學探針的開發 (II) 奈米藥物的合成與其在抗菌、抗凝血和抗癌的應用 (III) 奈米微結構的組裝和應用 (IV) 奈米材料於燃料電池、超級電容及二氧化碳還原的應用 |
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論文與著作 |
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Publications: 代表著作: 1. Anand, A.; Jian, H.-J.; Huang, H.-H.; Hean, L.E.; Li, Y.-J.; Lai*, J.-Y.; Chou, H.-D.; Kang, E.Y.-C.; Wu, W.-C.; Lai, C.-C.; Huang, C.-C.; H.-T. Chang* “Anti-angiogenic Carbon Nanovesicles Loaded with Bevacizumab for the Treatment of Age-related Macular Degeneration” Carbon 2023, 2023, 201, 362-370. 2. Lin, Y.-F.; Lin, Y.-S.; Huang, T.-Y.; Wei, S.-C.; Wu, R.-S.; Huang, C.-C.; Huang, Y-F.*; Chang, H.-T.* “Photoswitchable Carbon-dot Liposomes Mediate Catalytic Cascade Reactions for Amplified Dynamic Treatment of Tumor Cells” Journal of Colloid and Interface Sci. 2022, 628, 717–725. 3. Wu, R.-S.; Lin, Y.-S.; Nain, A.; Unnikrishnan, B.; Lin, Y.-F.; Yang, C.-R.; Chen, T.-H.; Huang, Y.-F.*; Huang, C.-C.; Chang, H.-T.* “Evaluation of Chemotherapeutic Response in Living Cells Using Subcellular Organelle‒Selective Amphipathic Carbon Dots” Biosens. Bioelectron. 2022, 211, 114362. 4. Sangili, A.; Unnikrishnan, B.; Nain, A.; Hsu, Y.-J.; Wu, R.-S.; Huang, C.-C. *; Chang, H.-T.* “Stable Carbon Encapsulated Titanium Carbide MXene Aqueous lnk for Fabricating High-performance Supercapacitors” Energy Storage Mater. 2022, 53, 51−61. 5. Lin, W.-J.; Lin, Y.-S.; Chang, H.-T.*; Unnikrishnan, B.; Huang, C.-C.* “Electrocatalytic CuBr@CuO Nanoparticles Based Salivary Glucose Probes” Biosens. Bioelectron. 2021, 194, 113610. 6. Wu, C.-W.; Unnikrishnan, B.; Chen, I.-W. P.; Harroun, S. G.; Chang, H.-T.*; Hung, C.-C.* “Excellent Oxidation Resistive MXene Aqueous Ink for Micro-Supercapacitor Application” Energy Storage Mater. 2020, 25, 563−571. 7. Xu, D.; Lin, Q.*; Chang, H.-T.* “Recent Advances and Sensing Applications of Carbon Dots” Small Methods 2019, 4, 1900387. 8. Chen, T.-H.; Chang, H.-T.* “Stable and Photoswitchable Carbon-Dot Liposome” ACS Appl. Mater. Inter. 2017, 9, 44259–44263. 9. Chen, P.-C.; Periasamy, A. P.; Harroun, S. G.; Wu, W.-P.; Chang, H.-T.* “Photoluminescence Sensing Systems Based on Copper, Gold and Silver Nanomaterials” Coord. Chem. Rev. 2016, 320, 129–138. 10. Chen, W.-Y.; Chang, H.-Y.; Lu, J.-K.; Huang, Y.-C.; Harroun, S. G.; Tseng, Y.-T.; Li, Y.-J.; Huang, C.-C.; Chang, H.-T.* “Self-Assembly of Antimicrobial Peptides on Gold Nanodots: Against Multidrug-Resistant Bacteria and Wound Healing Application” Adv. Funct. Mater. 2015, 25, 7189–7199. 11. Shih, C.-C.; Chen, P.-C.; Lin, G.-L.; Wang, C.-W.; Chang, H.-T.* “Optical and Electrochemical Applications of Silicon–Carbon Dots/Silicon Dioxide Nanocomposites” ACS Nano 2015, 9, 312–319. 12. Hsu, P.-C.; Chang, H.-T.* “Synthesis of High-Quality Carbon Nanodots from Hydrophilic Compounds: Role of Functional Groups” Chem. Commun. 2012, 3984–3986 13. Shiang, Y.-C.; Hsu, C.-L.; Huang, C.-C.*; Chang, H.-T.* “Gold Nanoparticles Presenting Hybridized Self-Assembled Aptamers That Exhibit Enhanced Inhibition of Thrombin” Angew. Chem. Int. Ed. 2011, 50, 7660–7665. 14. Yang, Z.; Chen, C.-Y.; Liu, C.-W.; Li, C.-L.; Chang, H.-T.* “Quantum Dot-Sensitized Solar Cells Featuring CuS/CoS Electrodes Provide 4.1% Efficiency” Adv. Energy Mater. 2011, 1, 259–264. 15. Chiang, C.-K.; Chen, W.-T.; Chang, H.-T.* “Nanoparticle-Based Mass Spectrometry for the Analysis of Biomolecules” Chem. Soc. Rev. 2011, 40, 1269–1281. 16. Lan, G.-Y.; Huang, C.-C.; Chang, H.-T.* “Silver Nanoclusters as Fluorescent Probes for Selective and Sensitive Detection of Copper Ions” Chem. Commun. 2010, 46, 1257–1259. 17. Yang, Z.; Chen, C.-Y.; Liu, C.-W.; Chang, H.-T.* “Electrocatalytic Sulfur Electrodes for CdS/CdSe Quantum Dot–Sensitized Solar Cells” Chem. Commun. 2010, 46, 5485–5487. 18. Huang, C.-C.; Yang, Z.; Lee, K.-H.; Chang, H.-T.* “Synthesis of Highly Fluorescent Gold Nanoparticles for Sensing Mercury(II)” Angew. Chem. Int. Ed. 2007, 46, 6824-6828. 19. Lin, Y.-W.; Tseng, W.-L.*; Chang, H.-T.* “Using a Layer-by-Layer Assembly Technique to Fabricate Multicolored-Light-Emitting Films of CdSe@CdS and CdTe Quantum Dots” Adv. Mater. 2006, 18, 1381-1386. 20. Huang, C.-C.; Chang, H.-T.* “Selective Gold Nanoparticle-Based “Turn-On” Fluorescent Sensors for Detection of Mercury(II) in Aqueous Solution” Anal. Chem. 2006, 78, 8332–8338.
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