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徐錦源(Chin-Yuan Hsu)

徐錦源 (Chin-Yuan Hsu)




清華大學博士(Ph.D. National Tsing Hau University, Taiwan)



+886-3-211-8800 ext.3402





+886-3-211-8800 ext. 3416




1. The mechanisms of aging and lifespan extension in honeybees.

2. The mechanism of lifespan extension at ambient temperature reduction.

3. Anti-aging drugs screen.



  1. Lu CY, Qiu JT, Hsu CY* (2018) Cellular energy metabolism is maintained during aging in long-living queen bees. Arch. Insect Biochem. Physiol. Doi:10.1002/arch.21468.
  2. Lu CY, Chuang YL, Hsu CY* (2017) Aging results in a decline in cellular energy metabolism in the trophocytes and oenocytes of worker honeybees (Apis mellifera). Apidologie 48:761-775.
  3. Hsu CY*, Qiu JT, Chan YP, (2016) Cellular degradation activity is maintained during aging in long-living queen bees. Biogerontology 17:829-840.
  4. Lu CY, Hsu CY* (2015) Ambient temperature reduction extends lifespan via activating cellular degradation activity in an annual fish (Nothobranchius rachovii). Age doi:10.1007/s11357-015-9775-z.
  5. Hsu CY*, Lu CY (2015) Mitochondrial energy utilization maintains young status in the trophocytes and fat cells of old queen honeybees. Apidologie doi:10.1007/s13592-015-0348-z.
  6. Hsu CY*, Hu TH (2014) Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees. Biogerontology 15:389-400.
  7. Hsu CY*, Chuang YL (2014) Changes in energy-regulated molecules in the trophocytes and fat cells of young and old worker honeybees. J. Gerontol. Ser. A Biol. Sci. Med. Sci. 69:955-964.
  8. Hsu CY*, Hsieh YS (2014) Oxidative stress decreases in the trophocytes and fat cells of worker honeybees during aging. Biogerontology 15:129-137.
  9. Hsu CY*, Chuang YL, Chan YP (2014) Changes in cellular degradation activity in young and old worker honeybees (Apis mellifera) Exp. Gerontol. 50:128-136.
  10. Hsieh YS, Hsu CY* (2013) Oxidative stress and anti-oxidant enzyme activities in the trophocytes and fat cells of queen honeybees (Apis mellifera). Rejuv. Res. 16:295-303.
  11. Chuang YL, Hsu CY* (2013) Changes in mitochondrial energy utilization in young and old worker honeybees. Age 35:1867-1879.
  12. Hsu CY*, Chan YP (2013) The use of honeybees reared in a thermostatic chamber for aging studies. Age 35:149-158.
  13. Hsieh YS, Hsu CY* (2011) The changes of age-related molecules in the trophocytes and fat cells of queen honeybees (Apis mellifera). Apidologie 42:728-739.
  14. Hsu CY*, Chan Y.P. (2011) Identification and localization of proteins associated with biomineralization in the iron deposition vesicles of honeybees (Apis mellifera). PLoS ONE 6(4):e19088. doi:10.1371/journal.pone.0019088
  15. Hsieh YS, Hsu CY* (2011) Honeybee trophocytes and fat cells as target cells for cellular senescence studies. Exp. Gerontol. 46:233-240.
  16. Hsu CY*, Chiu YC (2009) Ambient temperature influences aging in an annual fish (Nothobranchius rachovii). Aging Cell 8:726-737.
  17. Hsu CY*, Chiu YC, Hsu WL, Chan YP (2008) Age-related markers assayed at different developmental stages of the annual fish Nothobranchius rachovii. J. Gerontol. Ser. A Biol. Sci. Med. Sci. 63A:1267-1276.
  18. Hsu CY*) (2008) Antioxidant activity of extracts from Pyrrosia petiolosa. Fitoterapia 79:64-66.
  19. Hsu CY*, Ko FY, Li CW, Fann K, Lue JT (2007) Magnetoreception system in honeybees (Apis mellifera). PLoS ONE 2(4): e395. doi:10.1371/journal.pone.0000395.
  20. Hsu CY* (2004) The processes of iron deposition in the common hornet (Vespa affinis). Biol. Cell 96:529-537.
  21. Liou ML, Hsu CY* (1998) Japanese encephalitis virus transports across the cerebral blood vessels by endocytosis in mouse brain. Cell & Tissue Res. 293:389-394.
  22. Hsu CY, Li CW (1994) Magnetoreception in honeybees (Apis mellifera). Science 265:95-97.
  23. Hsu CY, Li CW (1993) The ultrastructure and formation of iron granules in the honey bee (Apis mellifera). J. Exp. Biol. 180:1-13.